(2019) Therapeutic potential of α-and β-pinene: A miracle gift of nature. Biomolecules. ISSN 2218273X (ISSN)
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Abstract
α-and β-pinene are well-known representatives of the monoterpenes group, and are found in many plants’ essential oils. A wide range of pharmacological activities have been reported, including antibiotic resistance modulation, anticoagulant, antitumor, antimicrobial, antimalarial, antioxidant, anti-inflammatory, anti-Leishmania, and analgesic effects. This article aims to summarize the most prominent effects of α-and β-pinene, namely their cytogenetic, gastroprotective, anxiolytic, cytoprotective, anticonvulsant, and neuroprotective effects, as well as their effects against H2O2-stimulated oxidative stress, pancreatitis, stress-stimulated hyperthermia, and pulpal pain. Finally, we will also discuss the bioavailability, administration, as well as their biological activity and clinical applications. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
| Item Type: | Article |
|---|---|
| Keywords: | Bioavailability Clinical studies Cytotoxicity Pharmacological activities α-pinene β-pinene benzodiazepine receptor beta pinene caspase 3 cineole ciprofloxacin erythromycin ethidium bromide limonene paclitaxel pinene piperazine ranitidine thromboxane A2 triclosan allergic rhinitis analgesic activity antiallergic activity antibiotic resistance anticoagulation antiinflammatory activity antileishmanial activity antimalarial activity antimicrobial activity antineoplastic activity antioxidant activity bacterium culture biological activity broth dilution Campylobacter jejuni cancer growth cancer survival cell cycle arrest cell protection cytogenetics DNA microarray drug activity electroencephalogram endocarditis enzyme linked immunosorbent assay Eucalyptus tereticornis gastroenteritis genomic instability Helicobacter pylori human hyperthermia immunoglobulin A nephropathy larvicidal activity mass fragmentography melanoma methicillin resistant Staphylococcus aureus minimum inhibitory concentration molecular model neuroprotection Nocardia non small cell lung cancer nonhuman ovary cancer oxidative stress pancreatitis Pistacia atlantica receptor binding Review Rhizopus oryzae sleep stomach emptying survival rate thrombin time thrombocyte aggregation tooth pain tranquilizing activity |
| Divisions: | |
| Journal or Publication Title: | Biomolecules |
| Journal Index: | Scopus |
| Volume: | 9 |
| Number: | 11 |
| Identification Number: | https://doi.org/10.3390/biom9110738 |
| ISSN: | 2218273X (ISSN) |
| Depositing User: | مهندس مهدی شریفی |
| URI: | http://eprints.mubam.ac.ir/id/eprint/934 |
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