Repository of Research and Investigative Information

Repository of Research and Investigative Information

Bam University of Medical Sciences

Voltammetric detection of gliclazide and glibenclamide with graphite screen-printed electrode modified with nanopetal-structured MoWS2

(2020) Voltammetric detection of gliclazide and glibenclamide with graphite screen-printed electrode modified with nanopetal-structured MoWS2. Research on Chemical Intermediates. pp. 837-852. ISSN 0922-6168

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Abstract

An oversimplified and sensitive sensor based on MoWS2-modified screen-printed electrode (MoWS2/SPE) was designed in this study for detecting gliclazide (GLZ) and glibenclamide (GLB) that are two widespread employed drugs in treating noninsulin-dependent diabetes mellitus. MoWS2 exhibited very good electrocatalytic activities toward oxidation of GLZ and GLB in comparison with bare SPE in 0.1M PBS, and the isolated capacities of oxidation peak assured concurrent determination of GLZ with widespread linear range between 0.06 and 500.0 mu M. Determination limit of GLZ has been 18.0 nM (S/N = 3). MoWS2/SPE has good steadiness, repeatability, and reproducibility. This procedure has had a successful application in detecting GLZ and GLB in their biological and pharmaceutical specimens with acceptable recovery.

Item Type: Article
Keywords: Gliclazide Glibenclamide MoWS2 composite Graphite screen-printed electrode carbon nanotubes sensor nanoparticles liquid sulfonylureas epinephrine nanosheets dopamine removal samples Chemistry
Divisions:
Page Range: pp. 837-852
Journal or Publication Title: Research on Chemical Intermediates
Journal Index: ISI
Volume: 46
Number: 1
Identification Number: https://doi.org/10.1007/s11164-019-03993-z
ISSN: 0922-6168
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mubam.ac.ir/id/eprint/857

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