(2020) The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action. Frontiers in Pharmacology. p. 20. ISSN 1663-9812
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Abstract
Anthocyanins are natural phenolic pigments with biological activity. They are well-known to have potent antioxidant and antiinflammatory activity, which explains the various biological effects reported for these substances suggesting their antidiabetic and anticancer activities, and their role in cardiovascular and neuroprotective prevention. This review aims to comprehensively analyze different studies performed on this class of compounds, their bioavailability and their therapeutic potential. An in-depth look in preclinical,in vitroandin vivo, and clinical studies indicates the preventive effects of anthocyanins on cardioprotection, neuroprotection, antiobesity as well as their antidiabetes and anticancer effects.
Item Type: | Article |
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Keywords: | anthocyanins biodisponibility neuroprotective cardioprotective antiobesity antidiabetic antioxidant anticancer high-fat-diet induced oxidative stress cardiovascular-disease mortality activated protein-kinase c-reactive protein oryza-sativa l. cells in-vitro nf-kappa-b insulin-resistance signaling pathways Pharmacology & Pharmacy |
Divisions: | |
Page Range: | p. 20 |
Journal or Publication Title: | Frontiers in Pharmacology |
Journal Index: | ISI |
Volume: | 11 |
Identification Number: | https://doi.org/10.3389/fphar.2020.01300 |
ISSN: | 1663-9812 |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.mubam.ac.ir/id/eprint/1116 |
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