Repository of Research and Investigative Information

Repository of Research and Investigative Information

Bam University of Medical Sciences

The Therapeutic Potential of the Labdane Diterpenoid Forskolin

(2019) The Therapeutic Potential of the Labdane Diterpenoid Forskolin. Applied Sciences-Basel. p. 13.

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Abstract

Forskolin is mainly found in the root of a plant called Coleus forskohlii (Willd.) Briq., which has been used in the traditional medicine of Indian Ayurvedic and Southeast Asia since ancient times. Forskolin is responsible for the pharmacological activity of this species. Forskolin is a labdane diterpenoid with a wide biological effect. Several studies suggested a positive role of forskolin on heart complications, respiratory disorders, high blood pressure, obesity, and asthma. There are numerous clinical and pre-clinical studies representing the effect of forskolin on the above-mentioned disorders but more clinical studies need to be performed to support its efficacy.

Item Type: Article
Keywords: forskolin plant secondary metabolites Coleus forskohlii cAMP pathway coleus-forskohlii cyclic-amp secondary metabolites terpene synthases asthma attacks muscle-cells camp biosynthesis protein phosphodiesterase Chemistry Engineering Materials Science Physics
Divisions:
Page Range: p. 13
Journal or Publication Title: Applied Sciences-Basel
Journal Index: ISI
Volume: 9
Number: 19
Identification Number: https://doi.org/10.3390/app9194089
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mubam.ac.ir/id/eprint/886

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