Abstract

Here in, a novel method for manufacturing selenium oxide nanoparticles (SeO2-NPs) was presented, which includes the use of sodium selenite (Na2SeO3), gelatin, and ascorbic acid as selenium precursor, stabilizing and reducing agents, respectively. The prepared SeO2-NPs have been characterization using field FESEM, XRD, and FTIR techniques. The presence of stable spherical SeO2-NPs with an average size of < 25 nm is shown by the results. The XRD pattern of SeO2-NPs shows a hexagonal crystal structure. The goal of this article was to study two features of SeO2-NPs, containing antifungal and photocatalytic activities. The antifungal examinations on Trichophyton tonsurans, T. benhamiae, T. rubrum, T. interdigitale, Microsporum canis, T. mentagrophytes, M. fulvum, and Epidermophyton floccosum have displayed the elegant functionality of nanoparticles in the role of an antifungal drug. In the presence of SeO2-NPs, about 60 of methylene blue (MB) was degraded after 120 min UV-irradiation that it's indicative of the acceptable photocatalytic property of SeO2-NPs. In Vitro cytotoxicity, findings on colorectal cancer SW 480 cells have revealed non-toxic even in concentrations that enclosed up to 100 mu g/mL in the MTT assay.