Abstract

To compare two samples of Bipolar patients presenting in mixed and manic episodes to assess their difference in terms of anxiety, depression and functioning. The sample included 94 patients who were admitted to the Shahid Beheshti mental hospital of Kerman Iran during autumn, winter (2007) and spring (2008) and were firmly diagnosed suffering from bipolar disorder type-I based on DSM-IV framework. Then they were grouped under the two category of manic episode (48 Patients) and mixed episode (46 Patients). All patients were evaluated by the Hamilton's Rating Scale for Depression (HRSD) and the Hamilton's Anxiety Rating Scale (HARS). The patients' functionality was rated during their illness and for the period of 6 months prior to their admittance using "Global Assessment of Functioning" (GAF) scoring system. The average of both Hamilton's Depression and Anxiety rates in bipolar mixed patients were significantly higher than manic patients. The patient's functionality rate at the time of admission was reduced noticeably for both groups but the functionality between both groups while they were admitted to the hospital did not show a significant difference. Mixed patients may suffer from anxiety and depression more than manic ones, but both of these groups have impaired functionality.