Repository of Research and Investigative Information

Repository of Research and Investigative Information

Bam University of Medical Sciences

Fabrication of electrochemical nanosensor based on carbon paste electrode modified with graphene oxide nano-ribbons and 3-(4′-amino-3′-hydroxy-biphenyl-4-yl)-acrylic acid for simultaneous detection of carbidopa and droxidopa

(2019) Fabrication of electrochemical nanosensor based on carbon paste electrode modified with graphene oxide nano-ribbons and 3-(4′-amino-3′-hydroxy-biphenyl-4-yl)-acrylic acid for simultaneous detection of carbidopa and droxidopa. Research on Chemical Intermediates. ISSN 09226168 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Bulk modification of carbon paste electrode (CPE) with graphene oxide nanoribbon and 3-(4′-amino-3′-hydroxy-biphenyl-4-yl) -acrylic acid (3,4′-AA-GONR/CPE) was used to develop a new electro-chemical sensor for sensitive determination of droxidopa and carbidopa at physiological pH. Chronoamperometry, differential pulse voltammetry, and cyclic voltammetry were employed to evaluate electro-chemical responses of as-prepared modified electrodes. A linear dependence of oxidation peak current on the concentration of droxidopa within a range between 0.02 and 300.0 μM was also observed with determination limit of 10.0 nM (S/N = 3). Desirable reproducibility, stability, and selectivity were seen in as-prepared 3,4′-AA-GONR/CPE, implying hopeful uses for concurrent detection of droxidopa and carbidopa. © 2019, Springer Nature B.V.

Item Type: Article
Keywords: Carbidopa Carbon paste electrode Droxidopa Graphene oxide nanoribbons Ascorbic acid Carboxylic acids Chemical modification Chronoamperometry Cyclic voltammetry Graphene Nanoribbons pH Differential pulse voltammetry Graphene oxide nanoribbon Linear dependence Modified electrodes Simultaneous detection Electrochemical electrodes
Divisions:
Journal or Publication Title: Research on Chemical Intermediates
Journal Index: Scopus
Identification Number: https://doi.org/10.1007/s11164-019-03908-y
ISSN: 09226168 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.mubam.ac.ir/id/eprint/741

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