Abstract

In this study, we combined the advantages of good conductivity, small size, large surface area, and the catalytic property of La 3+ /Co 3 O 4 nanoflowers to fabricate an electrochemical sensor sensitive for determination of vitamin B 6 in real samples. La 3+ /Co 3 O 4 nanoflowers were synthesized by a co-precipitation method that is a convenient, environment-friendly, and inexpensive process. The synthesized nanoflowers were characterized by SEM. A simple and sensitive sensor based on graphite screen printed electrode (GSPE) modified by La 3+ /Co 3 O 4 nanoflowers was developed for the electrochemical determination of vitamin B 6 . The electrochemical behavior of vitamin B 6 was studied in 0.1 M phosphate buffer solution (PBS) using cyclic voltammetry (CV), chronoamperometry (CHA), and differential pulse voltammetry (DPV). The modified electrode (La 3+ /Co 3 O 4 NFs/GSPE) showed excellent electrocatalytic activity and remarkable sensitivity towards the oxidation of vitamin B 6 . The fabricated sensor displayed good operating characteristics including low detection limit, and a wide linear dynamic range for the detection of vitamin B 6 . Using La 3+ /Co 3 O 4 NFs/GSPE as the working electrode, a linear dynamic range between 1.0-600.0 μM and a limit of detection of 0.4 μM were obtained. Finally, reliability and accuracy of the proposed sensor were studied in real samples. © 2019, Iranian Chemical Society.