Abstract

A Cu(II) nanocomplex, CuCl2(salophen).H2O salophen=ophenylenediaminebis( salicylidenaminato), was synthesized. The electrochemical properties of the as-prepared Cu(II) nanocomplex modified graphite screen printed electrode (Cu/SPE) were investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Moreover, as a nanosensor for the determination of epinephrine the Cu/SPE exhibited excellent electrocatalytic activity for the oxidation of epinephrine with a faster electrontransfer rate. The DPV technique was used for the trace determination of epinephrine. The dependence of current vs. concentration was linear from 10.0 to 600.0 mu M with a regression coefficient of 0.9975, and the detection limit of epinephrine was 2.5 +/- 0.05 mu M. Finally, the method was applied to the selective and precise analysis of epinephrine in epinephrine injection.