(2018) Synergic Effect of Cu(II) Nanocomplex for the Fabrication of Highly Sensitive Voltammetric Sensor for Levodopa Determination. Analytical & Bioanalytical Electrochemistry. pp. 292-301. ISSN 2008-4226
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Abstract
A novel modified graphite screen printed electrode (SPE) is prepared as an electrochemical sensor for determination of levodopa. The experimental results suggest that a screen printed electrode (SPE) modified with Cu(II) nanocomplex, CuCl2(salophen). H2O (salophen= o-phenylenediaminebis(salicylidenaminato)), accelerates the electron transfer reactions of levodopa. The fabricated sensor revealed some advantages such as convenient preparation, good stability and high sensitivity. The DPV data in 0.1 M phosphate buffer solution (PBS) (pH 7.0) allowed a method to be developed for the determination of levodopa concentrations in the ranges 5.0-900.0 mu M, with the detection limits of 0.9 mu M. The proposed method was successfully applied to determinations of levodopa in urine samples.
Item Type: | Article |
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Keywords: | Levodopa Cu(II) nanocomplex Graphite screen printed electrode Voltammetry carbon-paste electrode continuous cyclic voltammetry screen-printed electrodes uric-acid electrochemical sensor ascorbic-acid folic-acid parkinsons-disease ionic liquids epinephrine Electrochemistry |
Divisions: | |
Page Range: | pp. 292-301 |
Journal or Publication Title: | Analytical & Bioanalytical Electrochemistry |
Journal Index: | ISI |
Volume: | 10 |
Number: | 3 |
ISSN: | 2008-4226 |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.mubam.ac.ir/id/eprint/565 |
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