Abstract

Electrochemical behaviors of carbidopa at the surface of the graphite screen printed electrode (SPE) modified with Cu(II) nanocomplex, CuCl2(salophen). H2O (salophen=o-phenylenediaminebis(salicylidenaminato)) were studied. The oxidation peak potential of the carbidopa at a surface of Cu/SPE appeared at 360 mV that was about 100 mV lower than the oxidation peak potential at the surface of the traditional SPE under similar condition. On other hand, the oxidation peak current was increased for about two times at the surface of Cu/SPE compared to SPE. The linear response range and detection limit were found to be 0.5-700 mu M and 0.1 mu M, respectively. The proposed sensor was successfully applied for the determination of carbidopa in real samples.