Abstract

NiFe2O4 nanoparticles were successfully applied at a screen printed electrode (NiFe2O4/SPE). At first, NiFe2O4 nanoparticles were deposited on the SPE. This new modified electrode system was characterized by cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV). NiFe2O4/SPE was used for simultaneous determination of serotonin and norepinephrine. It was observed that an electrode with electrochemical deposited of NiFe2O4 nanoparticles has higher electrocatalytic activity for the oxidation of serotonin. Differential pulse voltammetry exhibited a linear dynamic range over the concentration range of 0.1-300.0 mu M and a detection limit (3s) of 0.07 mu M for serotonin in the optimum conditions. Finally, DPV was used for simultaneous determination of serotonin and norepinephrine and their detection real samples.